This study is to investigate the correlations among Sanjian (LI3), Hegu (LI4), and Yangxi (LI5) acupoints and their corresponding\nnonacupoints on the Yangming Large Intestine Meridian of Hand before and after laser irradiation using optical coherence\ntomography (OCT) and diffuse reflectance spectra. The experiment was conducted on 10 healthy people. A 658 nm laser with\n50mW output power was used for irradiating LI4, LI5 acupoints and their corresponding nonacupoints. As to LI4 acupoint with\nlaser irradiation for duration of 15 or 45 minutes, the OCT backscattered light intensities of LI4 and LI5 acupoints increased\nsignificantly, and the reflectance intensities (RIs) of the LI3, LI4, and LI5 acupoints decreased significantly. As to LI5 acupoint\nwith laser irradiation for duration of 15 or 45 minutes, the changes of OCT backscattered light intensities of the corresponding\nirradiated acupoint and LI4 acupoint increased significantly, and the RIs decreased significantly. However, the OCT backscattered\nlight intensities and RIs for their nonacupoints were almost not changed. The results show that an association exists between two\nadjacent same-meridian acupoints on the same meridian after laser-needle acupuncture to some extent.
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